Replication characteristics of equine herpesvirus 1 and equine herpesvirus 3: comparative analysis using ex vivo tissue cultures
نویسندگان
چکیده
منابع مشابه
Replication characteristics of equine herpesvirus 1 and equine herpesvirus 3: comparative analysis using ex vivo tissue cultures
Replication kinetics and invasion characteristics of equine herpesvirus-1 and -3 (EHV-1/-3) in nasal and vaginal mucosae were compared using explants. The explants were cultured during 96 h with little change in viability. The tissues were inoculated with EHV-1 03P37 (neuropathogenic), 97P70 (abortigenic) and EHV-3 04P57, collected at 0, 24, 48 and 72 h post inoculation (pi) and stained for vir...
متن کاملEquine herpesvirus-1 consensus statement.
Equine herpesvirus-1 is a highly prevalent and frequently pathogenic infection of equids. The most serious clinical consequences of infection are abortion and equine herpesvirus myeloencephalopathy (EHM). In recent years, there has been an apparent increase in the incidence of EHM in North America, with serious consequences for horses and the horse industry. This consensus statement draws toget...
متن کاملEpidemiology of equine herpesvirus 2 (equine cytomegalovirus).
The epidemiology of equine herpesvirus 2 was examined by using restriction endonuclease DNA fingerprints to distinguish viruses isolated from two groups of horses. The first group consisted of three yearlings isolated from other horses but in contact with each other for 418 days, whereas the second comprised seven mares and their foals, which were sampled at monthly intervals from parturition u...
متن کاملA critical view on Equine Herpesvirus-1 and on Equine Herpesvirus-associated Myeloencephalopathy (EHM)
An infection with Equine herpesvirus type 1 (EHV-1), officially and by convention now called EQUID Herpesvirus, is the cause for Equine herpesvirus-associated Myeloencephalopathy or EHM. In 2008 the USDA declared this syndrome an ‘emerging disease’ among horse populations in the U.S.A., which indicates that EHM is perceived as an expanding problem that is observed more frequently when compared ...
متن کاملEquine herpesvirus 1 utilizes a novel herpesvirus entry receptor.
The well-described herpesvirus entry receptors HveA (TNFRSF14), HveB (nectin 2), and HveC (nectin 1) have been shown to mediate the entry of alphaherpesviruses. Our findings showed that the alphaherpesvirus equine herpesvirus 1 (EHV-1) efficiently entered and replicated in CHO-K1 cells that lack the entry receptors HveA, HveB, and HveC, demonstrating that EHV-1 utilizes a unique entry receptor....
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ژورنال
عنوان ژورنال: Veterinary Research
سال: 2016
ISSN: 1297-9716
DOI: 10.1186/s13567-016-0305-5